Most treatments and interventions for Opioid Use Disorder (OUD) require that individuals engage in interpersonal communication with their health service providers or individuals in their recovery support network. However, at the specific moment when people resume their misuse of opioids, they are often alone or with people who enable their substance use. This webinar will provide information on the utilization of paced breathing exercises, delivered by smartphone, for self-management of drug cravings, stress, and anxiety. This session will include an overview of just-in-time interventions for substance use disorders, the biological basis for paced-breathing effectiveness, and user experience results from a pilot study.