Dr. John Mariani, a Providers Clinical Support System Clinical expert, explains what a patient can expect when she begins taking naltrexone for the treatment of opioid use disorder.
The development of this educational resource was originally funded by the Substance Abuse and Mental Health Services Administration’s (SAMHSA’s) Providers Clinical Support System-Medications for Opioid Used Disorder (PCSS-MOUD), cooperative agreement no. 1H79TI086770, with the American Academy of Addiction Psychiatry (AAAP), ending September 29, 2026. AAAP adapted the resource for dissemination in perpetuity. The views expressed do not necessarily reflect the official policies of the Department of Health and Human Services, SAMHSA, nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.