Have you used any nalexogol in your practice for opioid induced constipation when senna, docusate and miralax has failed?
Yes I have used it, it is effective but often hard to get past insurance. I like to use lactulose when others have failed. I did not find any specific articles on buprenorphine and Nalexogel but articles showing efficacy for multiple agents on OIC. Literature suggests that OIC may be less in buprenorphine but I have seen it in about 30% of patients.
